RCZHWBE7
type: UserItem
resource: Road Runoff Characterization: Ecotoxicological Assessment Combined with (Non-)Target Screenings of Micropollutants for the Identification of Relevant Toxicants in the Dissolved Phase
access date: 2022-02-09 10:51:27
repository: www.mdpi.com
rights: http://creativecommons.org/licenses/by/3.0/
tagged: AutoTag
  label: HRMS
tagged: AutoTag
  label: ecotoxicity
tagged: AutoTag
  label: light–dark transition
tagged: AutoTag
  label: micropollutants
tagged: AutoTag
  label: mitochondria
tagged: AutoTag
  label: non-target screening
tagged: AutoTag
  label: road runoff
tagged: AutoTag
  label: stress
tagged: AutoTag
  label: zebrafish

Road Runoff Characterization: Ecotoxicological Assessment Combined with (Non-)Target Screenings of Micropollutants for the Identification of Relevant Toxicants in the Dissolved Phase
type: AcademicArticle
abstract: Road runoff (RR) is an important vector of micropollutants towards groundwater and soils, threatening the environment and ecosystems. Through combined chemical and biological approaches, the purpose of this study was to get insights on specific toxicants present in RR from two sites differing by their traffic intensity and their toxicological risk assessment. Non-target screening was performed by HRMS on RR dissolved phase. Ecotoxicological risk was evaluated in a zebrafish embryos model and on rat liver mitochondrial respiratory chain. Specific HRMS fingerprints were obtained for each site, reflecting their respective traffic intensities. Several micropollutants, including 1,3-diphenylguanidine (DPG) and benzotriazole (BZT) were identified in greater concentrations at the high-traffic site. The origin of DPG was confirmed by analyzing HRMS fingerprints from shredded tires. RR samples from each site, DPG and BZT were of relatively low toxicity (no mortality) to zebrafish embryos, but all generated distinct and marked stress responses in the light–dark transition test, while DPG/BZT mixes abolished this effect. The moderate-traffic RR and DPG inhibited mitochondrial complex I. Our study highlights (i) the unpredictability of pollutants cocktail effect and (ii) the importance of a multi-approaches strategy to characterize environmental matrices, essential for their management at the source and optimization of depollution devices.
pages: 511
doi: 10.3390/w14040511
short title: Road Runoff Characterization
language: en
extra: Number: 4
creator: Person
author list: Person
is part of: Issue
  date: 2022/1
  volume: 14
  issue: 4
  is part of: Water
    type: Journal
    publisher: Multidisciplinary Digital Publishing Institute
    issn: 2073-4441

Person
given name: Fidji
surname: Sandré

Person
given name: Nina
surname: Huynh

Person
given name: Marie-Christine
surname: Gromaire

Person
given name: Gilles
surname: Varrault

Person
given name: Christophe
surname: Morin

Person
given name: Régis
surname: Moilleron

Person
given name: Julien
surname: Le Roux

Person
given name: Laure
surname: Garrigue-Antar